I’ve been a huge fan of this serum for years now and in my opinion, there’s nothing quite like it. This study from 2008 attributes the formation of collagen mainly to Adapalene when used with a laser and other retinoids in mice: https://www.ncbi.nlm.nih.gov/pubmed/18301943, This study from 2012 examines also the effects Adapalene has on photoaging and gives, which is of interest, the amount of wrinkle reduction: "There were significant improvements in clinical grading of wrinkles (p < 0.01) with a reduction in mean severity score of 40% in forehead wrinkles, 52% in periorbital wrinkles, and 29% in perioral wrinkles. Can't say if its strong enough for anti-ageing or really severe acne, but if anyone wants to start on a gentler retinol then I highly highly recommend. I noticed a reduction in acne pretty quickly! Holy grail moisturizer reddit acne. After that amount of time I feel like my skin would be extremely dry? I'm glad that it seems to last a while! I didn't want to press too much, but I thiiiink they're using 1% "retinaldehyde + other stuff." To see the Sidebar Research Threads, go here. I purged immediately, giving me terrible acne on my chin and a few bumps on my cheeks. Experience & opinion: This product is silky smooth and absorbs nicely (matte). Search. Skin info: Sensitive, combo, very acne prone, cystic acne. I have a post about how the two helped my skin on my blog. This is a product I've been eyeing - retinaldehyde is very interesting. Happy Hump Day everyone! Now, I go makeup free all the time. Is it worth going for prescription retinoids for someone without acne? So RoC Retinol Correxion tends to get more favorable ⭐ reviews than Holy Grail Retinol Repair, as seen on the chart below. My acne has lessened tremendously. After about 4-5 months total, I was still getting a few cysts on my cheeks, though my chin was okay for the most part, with only a few small bumps here and there. I’m debating getting a bottle before the Online GST comes into effect.